We had huge atv tyres on a rancher 2 we scrapped.

BIggest problem we had was the front axles bending due to the extra forces, once we had new hardened ones made it went like a champ. The engine had plenty of grunt to push it still even with a trailer on it.

As for making the hubs, it required some imagineation, you cant use the original rims (as we found) because the cast alloy will just fall apart. (this really hurts)